socalfunplaces Chapter 492
Chapter 492
To talk about fecal transplantation, first of all, it is necessary to understand - what is the flora!
In the gastrointestinal tract of healthy people, there are thousands of kinds of bacteria. Together with the gastrointestinal organs, these bacteria play an important role in all aspects of human digestion, metabolism and immunity.
At birth, the gastrointestinal tract of a newborn is almost sterile.
As the diet begins, bacteria from the outside world are brought into the gastrointestinal tract, slowly building up the flora in the gut. Around the age of 3, these flora are already set.
If the intestinal flora changes and the flora is out of balance, the person may get sick.
At present, in the study of beneficial intestinal flora, there are more studies on bacteria such as bifidobacteria, Bacillus subtilis, and lactobacillus, but the vast majority of intestinal bacteria, in fact, the medical community does not know much about them.
Bifidobacteria, lactobacilli, etc., can synthesize a variety of vitamins necessary for human growth and development, such as B vitamins, vitamin K, niacin, pantothenic acid, etc., and can also use protein residues to synthesize essential amino acids, such as aspartine, phenylalanine, valine and threonine, etc., and participate in the metabolism of sugars and proteins, while also promoting the absorption of iron, magnesium, zinc and other mineral elements.
These nutrients play an important role in human health, and once deficient, they can cause a variety of diseases.
When antibiotics are used, while killing pathogenic bacteria, they will also kill beneficial bacteria in the intestines, and while treating diseases, they may also bring new diseases.
(PS: From the above, you can see why antibiotics cannot be abused!) ）
Under normal circumstances, the intestinal bacterial flora is usually in a balanced state, mutually restricting, and is a harmonious intestinal society.
If some factors change the intestinal flora, it can cause an imbalance in the intestinal immune system and cause disease.
For example, in this patient's "ulcerative colitis", the flora must have gone seriously wrong, and the immune system must have been destroyed in the eyes.
Not only constipation and diarrhea are related to the intestinal flora, it is currently believed that obesity, high blood pressure, many cancers, some autoimmune diseases, the occurrence and cure of these diseases, are inseparable from the influence of intestinal flora.
From the above theory,
A new idea was born:
"Eat to cure diseases"!
That is, "fecal transplantation"!
It is the transplantation of microbial flora of healthy human feces into the patient's intestine.
Method:
Fecal bacteria transplantation is to take 50 to 100 grams of healthy human stool, add normal saline to filter impurities, and obtain a nearly transparent liquid after repeated treatment.
Then, this liquid is sent to the patient's intestine through endoscopy or enema, and the bacteria grow in the patient's intestine, re-establishing the balance of flora and achieving the purpose of treating the disease.
(It can't be drunk because most bacteria can't pass the stomach acid level and will be killed by stomach acid.) ）
This treatment method has been implemented for many years, and it is widely used abroad for some difficult recurrent intestinal diseases.
In particular, the cure rate of "pseudomembranous enteritis" can reach 90%, and it rarely recurs.
Foreign experiments have also found that transplanting fecal bacteria from lean mice into the intestines of fat mice can change the metabolism of fat mice and treat the obesity of fat mice. (The Gospel of Future Fat)
In recent years, foreign countries have successively set up "manure banks", and their applications have become more and more extensive.
However, in China, there are no relevant laws and regulations.
Lin Feng gave the patient Mr. Chen a detailed science popularization of this "fecal transplant".
Mr. Chen: "........."
20 million viewers: "........."
"Strange new knowledge has been added again."
"Can it still be like this?"
"Awesome!"
"This medicine has a taste..."
"No wonder so many animals eat mom's."
"Have you eaten?" Chinese greetings work at any time. "
(A few hours later, 'Did You Eat' was on the top of the big search.) ）
At this time, the patient, Mr. Chen, felt a little difficult to accept this method at this time.
Everyone understands the truth.
But the really stinks!
And also eat!
Lin Feng said patiently: "In your current situation, antibiotics and hormones are used too much, and there must be a big problem with the intestinal flora, so even if this plan can't cure 'ulcerative colitis', it can still help you re-establish a healthy intestinal flora..."
Mr. Chen: "....................."
Finally, after thinking about it, I didn't seem to have much choice.
Seven or eight times a day more than a dozen times a day, and blood in the stool, has already made him miserable.
What is eating?
Anyway, it's all eaten in one go.
"Good! I agreed! "
Mr. Chen gritted his teeth and decided.
Next, it is necessary to arrange hospitalization.
Lin Feng needs to find time to find healthy feces, and there is no fecal bank in China, so he needs to take healthy feces from the body of a healthy, ten-year-old healthy teenager (too old to be old).
Where did this boy come from?
Find it from the relatives and children of colleagues.
......
Microflora, in fact, not only plays a very important role in adult intestinal digestion.
In newborns, it also plays an important role.
It also involves the difference between "vaginal delivery" and "caesarean section".
First of all, when the newborn is still in the mother's womb before birth, it is completely sterile. There are no parasites, no viruses, no bacteria, no fungi, and it's cleaner than a sterile operating table.
Most of the birth canal is full of beneficial bacteria (more than half of them are the same species, Lactobacillus, which produces a large amount of lactic acid, causing the entire environment to appear acidic and inhibiting the survival of other bacteria) (the result of thousands of years of evolution? ）
If the birth is vaginal: the baby's first contact is a large number of beneficial bacteria in the birth canal, and the first step at the birth moment is to let a large number of beneficial bacteria enter the baby's body, occupy a favorable position, and then resist other harmful bacteria after birth.
If a caesarean section: the baby directly loses this process, and comes into contact with the outside world, and the microbiota will be very complicated. Therefore, the resistance will be weaker than that of a baby born naturally.
A new study published in 2019 in the top academic journal Nature confirms that the mode of delivery is a major factor in determining the gut microbiota in the first few weeks of life. The analysis showed that although the gut microbiota of all newborns changed within the first month of life, babies born vaginally were more stable and less likely to change than those born by caesarean section.
......
Next patient,
This is a couple.
The husband and wife walked in, and the husband supported his wife.
"Dr. Lin... Can I turn off the live stream? "
The wife said a little embarrassed.
"Yes..."
Lin Feng signaled the live broadcast assistant to turn off the live broadcast.
Live broadcast audience: ".................."
The live video screen went black.
Lin Feng: "What's wrong?" "
Wife: "It's like this, I found gallstones when I went to the hospital for a stomachache three months ago, and then today I found that I was pregnant..."
Lin Feng: ".................."
This is troublesome.
Gallstones are still very painful and can conflict with pregnancy.
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ps: Today the update is relatively early, now in the hospital to accompany the birth, I cheer code tomorrow's manuscript ~~
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